The house is shown as a pink-orange two-story detached house with an attached garage, basement, and loft. On the ground floor, the front door leads straight into the hallway, with one arch in the wall to the left, leading to the sitting room, one to the right which leads into the dining room, a small cupboard and the stairs to the first floor. The sitting room and the dining room, have bay windows. At the back of the house is the living room and the kitchen, with stairs that lead to the basement.
The second story of the house has Marge and Homer's bedroom (with an ensuite bathroom), Bart's bedroom, Lisa's bedroom, Maggie's bedroom, a bathroom and some 'empty' rooms, often shown in inconsistent places in different episodes. On the landing, there is a hatch which leads to the attic.
The kitchen features a side corridor leading to the back of the garage and a rarely seen second living room.
The back garden of the house is surrounded by a wooden picket fence and a low box hedge, and features a patio and the treehouse that the Simpsons' annual "Treehouse of Horror" episodes take their name from.
The house is now five miles away from where it was first built due to "Plan B", where, to avoid pollution, the entire city was moved down the road. This is believed by some fans to explain some inconsistencies such as the layout of the basement.
The house itself is often shown as dilapidated; the walls are painted with lead paint, the roof leaks and in one "episode", the kitchen was so badly damaged that it needed to be rebuilt (the rebuilt kitchen is not considered part of the show's continuity). A running gag is that whenever the camera pans between floors or rooms, the interior of the walls are shown to be filled with dangerous and unusual items such as asbestos, toxic waste, hidden treasure and baby dinosaurs. However, it is usually kept neat by homemaker Marge. In one episode, it was described as a palace by Frank Grimes. In another episode, Moe Szyslak observed that it contained no silverfish.
The house frequently suffers major damage due to attacks, accidents and negligence, including:
Abraham Simpson crashing through the sitting room window in a car
All furnishings being stolen by an angry mob
At several times, being set ablaze by Homer including while burning his high school diploma and while skipping church.
The house's interior trashed by the Hell's Satan motorcycle gang, in the episode "Take My Wife, Sleaze."